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Chemical Structure : ML398
Catalog No.: PC-62128Not For Human Use, Lab Use Only.
ML398 (CID72737723) is a potent, selective, highly brain penetrant dopamine 4 (D4R) receptor antagonist with IC50/Ki of 130 nM/60 nM.
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ML398 (CID72737723) is a potent, selective, highly brain penetrant dopamine 4 (D4R) receptor antagonist with IC50/Ki of 130 nM/60 nM.
ML398 (CID72737723) shows excellent selectivity (>100-fold) against the other dopamine receptor subtypes (D1,2S,2L,3,5; >20 uM).
ML398 (CID72737723) reverses cocaine-induced hyperlocomotion at 10 mg/kg in vivo.
| M.Wt | 315.841 | |
| Formula | C19H22ClNO | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Berry CB, et al. ACS Med Chem Lett. 2014 Jul 9;5(9):1060-4.
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