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ML400

Chemical Structure : ML400

CAS No.: 1908414-42-5

ML400 (ML 400;ML-400)

Catalog No.: PC-60897Not For Human Use, Lab Use Only.

ML400 is a potent, selective, allosteric LMPTP inhibitor with IC50 of 1.68 uM, displays good selective against other phosphatases.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ML400 is a potent, selective, allosteric LMPTP inhibitor with IC50 of 1.68 uM, displays good selective against other phosphatases.
ML400 displays good cell-based activity as well as rodent pharmacokinetics.
ML400 is a valuable tool to explore the effects of selective LMPTP inhibition in vitro and in vivo.

Physicochemical Properties

M.Wt 375.516
Formula C24H29N3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(4-methoxyphenyl)-N-(3-(piperidin-1-yl)propyl)quinolin-4-amine

References

1. Stanford SM, et al. Nat Chem Biol. 2017 Jun;13(6):624-632.

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