Chemical Structure : MLN8054
CAS No.:
869363-13-3
MLN8054
(MLN-8054;MLN 8054)
Catalog No. : PC-42424Not For Human Use, Lab Use Only.
MLN8054 is a potent, selective, ATP-competitive, orally active Aurora A kinase inhibitor with IC50 of 4 nM.
Packing Price Stock Quantity 2 mg $48 In stock 0 1 2 3 4 5 5 mg $88 In stock 0 1 2 3 4 5 10 mg $138 In stock 0 1 2 3 4 5 25 mg $218 In stock 0 1 2 3 4 5 50 mg $358 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4242401
Biological Activity
MLN8054 is a potent, selective, ATP-competitive, orally active Aurora A kinase inhibitor with IC50 of 4 nM.
Physicochemical Properties
M.Wt
476.862
Formula
C25H15ClF2N4O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Benzoic acid, 4-[[9-chloro-7-(2,6-difluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-
References
1. Manfredi MG, et al. Proc Natl Acad Sci U S A
2. Hoar K, et al. Mol Cell Biol
3. Dar AA, et al. Cancer Res.
4. Macarulla T, et al. Mol Cancer Ther
Contact Us
sales@probechem.com
