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MLS6585

Chemical Structure : MLS6585

CAS No.: 389080-71-1

MLS6585 (MLS-6585;MLS 6585)

Catalog No.: PC-35533Not For Human Use, Lab Use Only.

MLS6585 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling and increase the affinity of dopamine for the D1 receptor with low micromolar potencies.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MLS6585 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling and increase the affinity of dopamine for the D1 receptor with low micromolar potencies.

Physicochemical Properties

M.Wt 357.472
Formula C19H23N3O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(6-(tert-butyl)-3-carbamoyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)isonicotinamide

References

1. Luderman KD, et al. Mol Pharmacol. 2018 Aug 1. pii: mol.118.113175.

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