MMPI-1154 |CAS:1382722-47-5 Probechem Biochemicals

Chemical Structure : MMPI-1154

MMPI-1154 (MMPI1154)

Catalog No.: PC-63509Not For Human Use, Lab Use Only.

MMPI-1154 is a small molecule MMP-2 inhibitor with IC50 of 10/6.6/13/1.8 uM for MMP1/2/9/13, respectively.

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Biological Activity

MMPI-1154 is a small molecule MMP-2 inhibitor with IC50 of 10/6.6/13/1.8 uM for MMP1/2/9/13, respectively.
MMPI-1154 shows significant cardio-cytoprotecion, significantly decreases infarct size when applied at 1 μM in an ex vivo model for acute myocardial infarction.

Physicochemical Properties

M.Wt	445.494
Formula	C26H24FN3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(((4-(benzyloxy)benzyl)(4-fluorobenzyl)amino)methyl)-1H-imidazole-4-carboxylic acid

References

1. Bencsik P, et al. Front Pharmacol. 2018 Apr 5;9:296.

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MMPI-1154 (MMPI1154)

Biological Activity

Physicochemical Properties

References

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