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Chemical Structure : MMPIP hydrochloride
CAS No.: 1215566-78-1
Catalog No.: PC-22271Not For Human Use, Lab Use Only.
MMPIP hydrochloride is a selective, allosteric metabotropic glutamate receptor 7 (mGluR7) antagonist / negative allosteric modulator with Kb value of 24-30 nM.
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| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $348 | In stock | |
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MMPIP hydrochloride is a selective, allosteric metabotropic glutamate receptor 7 (mGluR7) antagonist / negative allosteric modulator with Kb value of 24-30 nM.
MMPIP hydrochloride reversed antidepressant-like effects of AMN082 in rats.
MMPIP hydrochloride alleviates pain and normalizes affective and cognitive behavior in neuropathic mice.
| M.Wt | 369.81 | |
| Formula | C19H16ClN3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-ylisoxazolo[4,5-c]pyridin-4(5H)-one hydrochloride |
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1. Kotlinska JH, et al. Eur J Pharmacol. 2019 Sep 5;858:172512.
2. Palazzo E, et al. Pain. 2015 Jun;156(6):1060-1073.
3. Pałucha-Poniewiera A, et al. Behav Brain Res. 2013 Feb 1;238:109-12.
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