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Chemical Structure : MMSET-IN-1
Catalog No.: PC-62409Not For Human Use, Lab Use Only.
MMSET-IN-1 (NSD2 inhibitor 1) is a potent, selective epigenetic oncogene MMSET (aka NSD2 or WHSC1) inhibitor with Ki/IC50 of 1.6/3.3 uM.
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MMSET-IN-1 (NSD2 inhibitor 1) is a potent, selective epigenetic oncogene MMSET (aka NSD2 or WHSC1) inhibitor with Ki/IC50 of 1.6/3.3 uM.
MMSET-IN-1 shows sub-micromolar inhibition of SETD2 and promising selectivity against a panel of 13 other KMTs.
| M.Wt | 423.474 | |
| Formula | C18H29N7O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Tisi D, et al. ACS Chem Biol. 2016 Nov 18;11(11):3093-3105.
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