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MMT-160

Chemical Structure : MMT-160

CAS No.: 1639059-34-9

MMT-160 (MMT160)

Catalog No.: PC-38650Not For Human Use, Lab Use Only.

MMT-160 is a novel selective peroxisome proliferator-activated receptor γ (PPARγ) antagonist with IC50 of 0.17 uM, covalently binds to the PPARγ ligand binding domain (LBD) via Cys285.

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    Biological Activity

    MMT-160 is a novel selective peroxisome proliferator-activated receptor γ (PPARγ) antagonist with IC50 of 0.17 uM, covalently binds to the PPARγ ligand binding domain (LBD) via Cys285.

    Physicochemical Properties

    M.Wt 490.563
    Formula C30H26N4O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(5-(3-phenylpropiolamido)-2-propoxybenzyl)-4-(pyrimidin-2-yl)benzamide

    References

    1. Mami Yoshizawa, et al. Bioorg Med Chem Lett. 2022 May 15;64:128676.

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