MMT-160 | PPARγ inhibitor | Probechem Biochemicals

Chemical Structure : MMT-160

MMT-160 (MMT160)

Catalog No.: PC-38650Not For Human Use, Lab Use Only.

MMT-160 is a novel selective peroxisome proliferator-activated receptor γ (PPARγ) antagonist with IC50 of 0.17 uM, covalently binds to the PPARγ ligand binding domain (LBD) via Cys285.

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Biological Activity

MMT-160 is a novel selective peroxisome proliferator-activated receptor γ (PPARγ) antagonist with IC50 of 0.17 uM, covalently binds to the PPARγ ligand binding domain (LBD) via Cys285.

Physicochemical Properties

M.Wt	490.563
Formula	C30H26N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-(3-phenylpropiolamido)-2-propoxybenzyl)-4-(pyrimidin-2-yl)benzamide

References

1. Mami Yoshizawa, et al. Bioorg Med Chem Lett. 2022 May 15;64:128676.

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MMT-160 (MMT160)

Biological Activity

Physicochemical Properties

References

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