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Chemical Structure : MMV000848
Catalog No.: PC-23029Not For Human Use, Lab Use Only.
MMV000848 is a small molecule inhibitor of P. falciparum purine nucleoside phosphorylase (PfPNP, KD=1.52 uM) with EC50 of 0.1 uM against Plasmodium falciparum, also inhibits falcilysin (FLN) proteolytic activity.
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MMV000848 is a small molecule inhibitor of P. falciparum purine nucleoside phosphorylase (PfPNP, KD=1.52 uM) with EC50 of 0.1 uM against Plasmodium falciparum, also inhibits falcilysin (FLN) proteolytic activity.
| M.Wt | 308.43 | |
| Formula | C20H24N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Chung Z, et al. J Biol Chem. 2024 Jan;300(1):105586.
2. Wirjanata G, et al. Cell Chem Biol. 2024 Apr 18;31(4):743-759.e8.
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