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Chemical Structure : MMV006833
Catalog No.: PC-22542Not For Human Use, Lab Use Only.
MMV006833 (M-833) is a small molecule inhibitor of PfSTART1 with EC50 of 1.1 uM for Pf 3D7, binds to PfSTART1(WT) with KD of 42 nM, inhibits ring-stage development of Plasmodium falciparum, prevents PfSTART1 from expanding the vacuole membrane encasing the parasite after red blood cell invasion, thereby blocking parasite growth.
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MMV006833 (M-833) is a small molecule inhibitor of PfSTART1 with EC50 of 1.1 uM for Pf 3D7, binds to PfSTART1(WT) with KD of 42 nM, inhibits ring-stage development of Plasmodium falciparum, prevents PfSTART1 from expanding the vacuole membrane encasing the parasite after red blood cell invasion, thereby blocking parasite growth.
| M.Wt | 414.95 | |
| Formula | C19H27ClN2O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Madeline G Dans, et al. Nat Commun. 2024 Jun 18;15(1):5219.
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