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MMV026468

Chemical Structure : MMV026468

CAS No.: 1329674-83-0

MMV026468 (MMV 026468)

Catalog No.: PC-22744Not For Human Use, Lab Use Only.

MMV026468 is a highly potent, picomolar inhibitor of blood-stage Plasmodium falciparum, targets MEP isoprenoid precursor biosynthesis, inhibits first MEP enzyme DXS or steps prior to DXS such as regulation of the MEP pathway.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MMV026468 is a highly potent, picomolar inhibitor of blood-stage Plasmodium falciparum, targets MEP isoprenoid precursor biosynthesis, inhibits first MEP enzyme DXS or steps prior to DXS such as regulation of the MEP pathway.

Physicochemical Properties

M.Wt 310.78
Formula C18H15ClN2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

[4-[5-(3-Chloroanilino)pyridin-3-yl]phenyl]methanol

References

1. Stephanie Kabeche, et al. Antimicrob Agents Chemother. 2024 Jul 22:e0123823.

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