MMV1580853 | Antimalarial | Probechem Biochemicals

Chemical Structure : MMV1580853

CAS No.: 5352-53-4

MMV1580853 (BPH-1358, MMV 1580853)

Catalog No.: PC-22743Not For Human Use, Lab Use Only.

MMV1580853 (BPH-1358) is a potent and exceedingly fast-acting blood-stage antimalarial, inhibits human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor with IC50s of 1.8 μM and 110 nM, respectively.

Packing	Price	Stock
5 mg	$238	In stock
10 mg	$388	In stock
25 mg	$598	In stock
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Biological Activity

Physicochemical Properties

M.Wt	601.53
Formula	C32H30Cl2N6O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N4,N4'-bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)-[1,1'-biphenyl]-4,4'-dicarboxamide dihydrochloride

References

1. Ryan Choi, et al. PLoS One. 2021 Apr 22;16(4):e0250019.

2. Zhu W, et al. J Med Chem. 2015 Feb 12;58(3):1215-27.

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MMV1580853 (BPH-1358, MMV 1580853)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

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