Chemical Structure : MMV1580853
CAS No.: 5352-53-4
Catalog No.: PC-22743Not For Human Use, Lab Use Only.
MMV1580853 (BPH-1358) is a potent and exceedingly fast-acting blood-stage antimalarial, inhibits human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor with IC50s of 1.8 μM and 110 nM, respectively, is active against S. aureus in vitro (MIC, 250 ng/mL).
Packing | Price | Stock | Quantity |
---|---|---|---|
5 mg | $128 | In stock | |
10 mg | $198 | In stock | |
25 mg | $358 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
Bulk size, bulk discount!
Welcome credit card payment!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
MMV1580853 (BPH-1358) is a potent and exceedingly fast-acting blood-stage antimalarial, inhibits human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor with IC50s of 1.8 μM and 110 nM, respectively, is active against S. aureus in vitro (MIC, 250 ng/mL).
M.Wt | 601.53 | |
Formula | C32H30Cl2N6O2 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
N4,N4'-bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)-[1,1'-biphenyl]-4,4'-dicarboxamide dihydrochloride |
1. Ryan Choi, et al. PLoS One. 2021 Apr 22;16(4):e0250019.
2. Zhu W, et al. J Med Chem. 2015 Feb 12;58(3):1215-27.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright