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MMV675968

Chemical Structure : MMV675968

CAS No.: 159308-73-3

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MMV675968 (MMV 675968)

Catalog No.: PC-73100Not For Human Use, Lab Use Only.

MMV675968 is a potent, small molecule inhibitor of Toxoplasma gondii (T. gondii) with IC50 of 0.02 uM, via the pathogen box.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MMV675968 is a potent, small molecule inhibitor of Toxoplasma gondii (T. gondii) with IC50 of 0.02 uM, via the pathogen box.
    MMV675968 has been shown to be efficient against the planktonic form of C. albicans.
    MMV675968 showed an antiplasmodial activity against P. falciparum.
    MMV675968inhibited the growth of all four A. baumannii test strains with IC50 of 0.6-2.7 uM, IC90 of 0.7-3.9 uM, and MIC of 1.6-10 uM.

    Physicochemical Properties

    M.Wt 359.814
    Formula C17H18ClN5O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    5-chloro-6-(((2,5-dimethoxyphenyl)amino)methyl)quinazoline-2,4-diamine

    References

    1. Spalenka J, et al. Antimicrob Agents Chemother. 2018 Jan 25;62(2):e01640-17.

    2. Songsungthong W, et al. Sci Rep. 2019 Oct 30;9(1):15625.

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