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MN30

Chemical Structure : MN30

CAS No.: 173043-84-0

MN30 (Methyl-3,4-dephostatin, APOBEC3G inhibitor MN30)

Catalog No.: PC-62363Not For Human Use, Lab Use Only.

MN30 (Methyl-3,4-dephostatin, APOBEC3G inhibitor MN30) is a first-in-class, selectve small molecule inhibitor of the single-strand DNA cytosine deaminase APOBEC3G with IC50 of 9.1 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MN30 (Methyl-3,4-dephostatin, APOBEC3G inhibitor MN30) is a first-in-class, selectve small molecule inhibitor of the single-strand DNA cytosine deaminase APOBEC3G with IC50 of 9.1 uM.
    MN30 shows no significant activity against E. coli uracil DNA glycosylase (UDG), and APOBEC3A (IC50>200 uM).

    Physicochemical Properties

    M.Wt 168.152
    Formula C7H8N2O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(3,4-dihydroxyphenyl)-N-methylnitrous amide

    References

    1. Li M, et al. ACS Chem Biol. 2012 Mar 16;7(3):506-17.

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