MP-002 | FKBP12 ligand | Probechem Biochemicals

Chemical Structure : MP-002

MP-002 (AHK2)

Catalog No.: PC-28594Not For Human Use, Lab Use Only.

MP-002 (AHK2) is a triazole-based FKBP12 ligand, competes with rapamycin for the FKBP12 binding pocket, stabilizing the FKBP12/RyR interaction, rescues multiple premature aging phenotypes in dyotonic dystrophy type 1 (DM1) models.

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Biological Activity

Physicochemical Properties

M.Wt	292.40
Formula	C14H20N4OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-[2-(N,N-dimethylamino)ethyl]-4-[(4-methoxyphenyl)thiomethyl]-1H-1,2,3-triazole

References

1. Passannante R, et al. Biomedicines. 2023 Jan 18;11(2):253.

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MP-002 (AHK2)

Biological Activity

Physicochemical Properties

References

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