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MP07-66

Chemical Structure : MP07-66

CAS No.: 1938056-90-6

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MP07-66 (MP 07-66)

Catalog No.: PC-70156Not For Human Use, Lab Use Only.

MP07-66 is a novel FTY720 analog that acts as PP2A activator, disrupts the SET/PP2A interaction devoid of immunosuppressive effects leads to the reactivation of PP2A.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MP07-66 is a novel FTY720 analog that acts as PP2A activator, disrupts the SET/PP2A interaction devoid of immunosuppressive effects leads to the reactivation of PP2A.
MP07-66 triggers apoptosis of CLL cells, and the action of MP07-66 is synergistically amplified when used in combination with Src family kinase inhibitors.

Physicochemical Properties

M.Wt 323.477
Formula C19H33NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,2-diethoxy-N-(4-(hexyloxy)benzyl)ethan-1-amine

References

1. Zonta F, et al. Blood. 2015 Jun 11;125(24):3747-55.

2. Tibaldi E, et al. Haematologica. 2017 Aug;102(8):1401-1412.

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