MPEP hydrochloride

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Chemical Structure : MPEP hydrochloride

CAS No.: 219911-35-0

Catalog No.: PC-26040Not For Human Use, Lab Use Only.

MPEP hydrochloride is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor (mGluR5) antagonist with IC50 of 36 nM, has anxiolytic-or antidepressant-like effects.

Packing	Price	Stock
25 mg	$58	In stock
100 mg	$128	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MPEP hydrochloride is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor (mGluR5) antagonist with IC50 of 36 nM, has anxiolytic-or antidepressant-like effects.

Physicochemical Properties

M.Wt	229.71
Formula	C14H12ClN
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Methyl-6-(phenylethynyl)pyridine hydrochloride

References

1. F Gasparini, et al. Neuropharmacology. 1999 Oct;38(10):1493-503.

2. E Tatarczyńska, et al. Br J Pharmacol. 2001 Apr;132(7):1423-30.

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