MPK-09 |CAS:1431884-83-1 Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Apoptosis-MDM2-p53-MPK-09

Chemical Structure : MPK-09

MPK-09 (MPK09;MPK 09)

Catalog No.: PC-60182Not For Human Use, Lab Use Only.

A highly potent, selective mutant p53 (R175H, R249S, R273H, R273C) reactivator.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MPK-09 is a highly potent, selective mutant p53 (R175H, R249S, R273H, R273C) reactivator.
MPK-09 exhibits potent cytotoxic activity against BT474 (p53 E285K) cell line (IC50=0.6 uM) as compared to wt p53 A549 (IC50=2.8 uM) and HeLa (IC50 = 4 uM) cells.
MPK-09 enhances PARP cleavage, activates caspase 3 expressions and induces apoptosis.

Physicochemical Properties

M.Wt	418.53
Formula	C24H34O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2E)-4-[(4R,5S)-5-[(R)-(Hexyloxy)phenylmethyl]-2,2-dimethyl-1,3-dioxolan-4-yl]-4-oxo-2-butenoic acid ethyl ester

References

1. Metri PK, et al. ACS Chem Biol. 2013 Jul 19;8(7):1429-34.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

MPK-09 (MPK09;MPK 09)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.