MPO-IN-28 |CAS:37836-90-1 Probechem Biochemicals

Chemical Structure : MPO-IN-28

CAS No.: 37836-90-1

MPO-IN-28 (Myeloperoxidase inhibitor 28)

Catalog No.: PC-60357Not For Human Use, Lab Use Only.

MPO-IN-28 is a potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.

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5 mg	$78	In stock
10 mg	$118	In stock
25 mg	$218	In stock
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Biological Activity

MPO-IN-28 is a potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.
MPO-IN-28 shows 100-fold selectivity over LPO.
MPO-IN-28 inhibits the growth of normal human dermal fibroblast with IC50 of 17 uM.

Physicochemical Properties

M.Wt	231.259
Formula	C11H13N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(7-methoxy-4-methylquinazolin-2-yl)guanidine

References

1. Soubhye J, et al. J Med Chem. 2017 Jul 19. doi: 10.1021/acs.jmedchem.7b00285.

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MPO-IN-28 (Myeloperoxidase inhibitor 28)

Biological Activity

Physicochemical Properties

References

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