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MPO-IN-28

Chemical Structure : MPO-IN-28

CAS No.: 37836-90-1

MPO-IN-28 (Myeloperoxidase inhibitor 28)

Catalog No.: PC-60357Not For Human Use, Lab Use Only.

MPO-IN-28 is a potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MPO-IN-28 is a potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.
MPO-IN-28 shows 100-fold selectivity over LPO.
MPO-IN-28 inhibits the growth of normal human dermal fibroblast with IC50 of 17 uM.

Physicochemical Properties

M.Wt 231.259
Formula C11H13N5O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(7-methoxy-4-methylquinazolin-2-yl)guanidine

References

1. Soubhye J, et al. J Med Chem. 2017 Jul 19. doi: 10.1021/acs.jmedchem.7b00285.

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