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MR-409

Chemical Structure : MR-409

CAS No.: 1445155-39-4

MR-409 (MR 409, MR409)

Catalog No.: PC-28595Not For Human Use, Lab Use Only.

MR-409 (MR 409, MR409) is a synthetic GHRH analogue and growth hormone-releasing hormone receptor (GHRHR) agonist with binding IC50 of 1.01 nM in membrane GHRHR of human pituitary cells, exhibits high growth hormone-releasing potency.

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Biological Activity

MR-409 (MR 409, MR409) is a synthetic GHRH analogue and growth hormone-releasing hormone receptor (GHRHR) agonist with binding IC50 of 1.01 nM in membrane GHRHR of human pituitary cells, exhibits high growth hormone-releasing potency.

Physicochemical Properties

M.Wt 3395.91
Formula C153H252N44O43
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

{Asn-Me}-Tyr-{D-Ala}-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-{Orn}-Val-Leu-{Abu}-Gln-Leu-Ser-Ala-Arg-{Orn}-Leu-Leu-Gln-Asp-Ile-{Nle}-Asp-Arg-NHMe

References

1. Gesmundo I, et al. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):12033-12038.

2. Gomes SA, et al. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2834-9.

3. Cai R, et al. Peptides. 2014 Feb;52:104-12.

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