MRK-623 | GABAA α2/α3 agonist | Probechem Biochemicals

Chemical Structure : MRK-623

CAS No.: 461449-78-5

MRK-623 (MRK623)

Catalog No.: PC-62770Not For Human Use, Lab Use Only.

MRK-623 is a potent, α2/α3 subunit functionally selectivie GABAA receptor agonist with Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively.

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5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$328	In stock
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Biological Activity

MRK-623 is a potent, α2/α3 subunit functionally selectivie GABAA receptor agonist with Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively.

Physicochemical Properties

M.Wt	348.381
Formula	C20H17FN4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-(4-fluoro-3-pyridin-3-yl-phenyl)-imidazo(1,2-a)pyrimidin-7-yl)-propan-2-ol

References

1. Shinday NM, et al. Neuropsychopharmacology. 2013 May;38(6):1006-14.

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MRK-623 (MRK623)

Biological Activity

Physicochemical Properties

References

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