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MRK-623

Chemical Structure : MRK-623

CAS No.: 461449-78-5

MRK-623 (MRK623)

Catalog No.: PC-62770Not For Human Use, Lab Use Only.

MRK-623 is a potent, α2/α3 subunit functionally selectivie GABAA receptor agonist with Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively.

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Purity & Documentation Purity: 99.14% (HPLC) Select Batch:

Biological Activity

MRK-623 is a potent, α2/α3 subunit functionally selectivie GABAA receptor agonist with Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively.

Physicochemical Properties

M.Wt 348.381
Formula C20H17FN4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3-(4-fluoro-3-pyridin-3-yl-phenyl)-imidazo(1,2-a)pyrimidin-7-yl)-propan-2-ol

References

1. Shinday NM, et al. Neuropsychopharmacology. 2013 May;38(6):1006-14.

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