Chemical Structure : MRK-623
CAS No.: 461449-78-5
Catalog No.: PC-62770Not For Human Use, Lab Use Only.
MRK-623 is a potent, α2/α3 subunit functionally selectivie GABAA receptor agonist with Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively.
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MRK-623 is a potent, α2/α3 subunit functionally selectivie GABAA receptor agonist with Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively.
M.Wt | 348.381 | |
Formula | C20H17FN4O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-(3-(4-fluoro-3-pyridin-3-yl-phenyl)-imidazo(1,2-a)pyrimidin-7-yl)-propan-2-ol |
1. Shinday NM, et al. Neuropsychopharmacology. 2013 May;38(6):1006-14.
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