MRK-898 | GABA A modulator | Probechem Biochemicals

Chemical Structure : MRK-898

MRK-898 (MRK898)

Catalog No.: PC-21943Not For Human Use, Lab Use Only.

MRK-898 is an orally active GABA(A) receptor modulator, binds to α1, α2, α3 or α5 subunit of GABA(A) receptor with Ki values of 1.2 nM, 1.0 nM, 0.73 nM, and 0.50 nM, respectively.

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Biological Activity

MRK-898 is an orally active GABA(A) receptor modulator, binds to α1, α2, α3 or α5 subunit of GABA(A) receptor with Ki values of 1.2 nM, 1.0 nM, 0.73 nM, and 0.50 nM, respectively.

Physicochemical Properties

M.Wt	400.31
Formula	C20H9F5N4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	[1,1'-Biphenyl]-2-carbonitrile, 2',4-difluoro-5'-[7-(trifluoromethyl)imidazo[1,2-a]pyrimidin-3-yl]-

References

1. John R Atack, et al. Curr Top Med Chem. 2011;11(9):1176-202.

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MRK-898 (MRK898)

Biological Activity

Physicochemical Properties

References

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