MRL-SYKi

Chemical Structure : MRL-SYKi

Catalog No.: PC-20054Not For Human Use, Lab Use Only.

MRL-SYKi is a potent, selective inhibitor of Syk (Spleen tyrosine kinase) with IC50 of <100 nM, also potently inhibits ZAP70 (24 nM in vitro).

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Biological Activity

MRL-SYKi is a potent, selective inhibitor of Syk (Spleen tyrosine kinase) with IC50 of <100 nM, also potently inhibits ZAP70 (24 nM in vitro).

M.Wt	452.57
Formula	C24H28N4O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1S,4R)-4-hydroxy-2,2-dimethyl-4-(5-(3-methyl-5-((4-methylpyrimidin-2-yl)amino)phenyl)thiazol-2-yl)cyclohexane-1-carboxylic acid

1. Capener JL, et al. bioRxiv [Preprint]. 2024 Jun 13:2024.06.12.598544.