MRL-SYKi

Chemical Structure : MRL-SYKi

Catalog No.: PC-20054Not For Human Use, Lab Use Only.

MRL-SYKi is a potent, selective inhibitor of Syk (Spleen tyrosine kinase) with IC50 of <100 nM, also potently inhibits ZAP70 (24 nM in vitro).

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

MRL-SYKi is a potent, selective inhibitor of Syk (Spleen tyrosine kinase) with IC50 of <100 nM, also potently inhibits ZAP70 (24 nM in vitro).

M.Wt	452.57
Formula	C24H28N4O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1S,4R)-4-hydroxy-2,2-dimethyl-4-(5-(3-methyl-5-((4-methylpyrimidin-2-yl)amino)phenyl)thiazol-2-yl)cyclohexane-1-carboxylic acid

1. Capener JL, et al. bioRxiv [Preprint]. 2024 Jun 13:2024.06.12.598544.