Chemical Structure : MRS-1706
CAS No.: 264622-53-9
Catalog No.: PC-22753Not For Human Use, Lab Use Only.
MRS-1706 (MRS1706) is a potent and selective adenosine A2B receptor (A2BR) inverse agonist / antagonist with Ki of 1.39 nM, >100-fold selective over A2A, A1 and A3 receptors.
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MRS-1706 (MRS1706) is a potent and selective adenosine A2B receptor (A2BR) inverse agonist / antagonist with Ki of 1.39 nM, >100-fold selective over A2A, A1 and A3 receptors.
M.Wt | 503.56 | |
Formula | C27H29N5O5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-(4-Acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)phenoxy)acetamide |
1. Quintas C, et al. Neuroscience. 2011 May 19;182:32-42.
2. Breschi MC, et al. Eur J Pharmacol. 2007 Dec 1;575(1-3):149-57.
3. Li Q, et al. J Pharmacol Exp Ther. 2007 Feb;320(2):637-45.
4. Trincavelli ML, et al. J Neurochem. 2004 Dec;91(5):1180-90.
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