MRS2485 |CAS:859724-34-8 Probechem Biochemicals

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Chemical Structure : MRS2485

MRS2485 (MRS-2485)

Catalog No.: PC-62065Not For Human Use, Lab Use Only.

MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity.

Physicochemical Properties

M.Wt	420.391
Formula	C22H30BrNO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-1-(8-((2-phenylpropanoyl)oxy)octyl)pyridin-1-ium bromide

References

1. Diaz JC, et al. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3348-53.

2. Shafrir Y, et al. Proteins. 2010 Dec;78(16):3473-87.

3. Tchilibon S, et al. Biochem Pharmacol. 2005 Aug 1;70(3):381-93.

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MRS2485 (MRS-2485)

Biological Activity

Physicochemical Properties

References

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