Chemical Structure : MRS2485
Catalog No.: PC-62065Not For Human Use, Lab Use Only.
MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity..
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MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity.
M.Wt | 420.391 | |
Formula | C22H30BrNO2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Diaz JC, et al. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3348-53.
2. Shafrir Y, et al. Proteins. 2010 Dec;78(16):3473-87.
3. Tchilibon S, et al. Biochem Pharmacol. 2005 Aug 1;70(3):381-93.
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