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MRS2485

Chemical Structure : MRS2485

CAS No.: 859724-34-8

MRS2485 (MRS-2485)

Catalog No.: PC-62065Not For Human Use, Lab Use Only.

MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity.

    Physicochemical Properties

    M.Wt 420.391
    Formula C22H30BrNO2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-1-(8-((2-phenylpropanoyl)oxy)octyl)pyridin-1-ium bromide

    References

    1. Diaz JC, et al. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3348-53.

    2. Shafrir Y, et al. Proteins. 2010 Dec;78(16):3473-87.

    3. Tchilibon S, et al. Biochem Pharmacol. 2005 Aug 1;70(3):381-93.

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