MS3745 | G9a-like protein inhibitor | Probechem Biochemicals

Chemical Structure : MS3745

MS3745 (MS 3745, MS-3745)

Catalog No.: PC-22923Not For Human Use, Lab Use Only.

MS3745 is a potent and selective inhibitor of protein lysine methyltransferase G9a-like protein (GLP) with IC50 of 4 nM, 65-fold selective over G9a.

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Biological Activity

MS3745 is a potent and selective inhibitor of protein lysine methyltransferase G9a-like protein (GLP) with IC50 of 4 nM, 65-fold selective over G9a.

Physicochemical Properties

M.Wt	399.54
Formula	C22H33N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N2-Cyclopentyl-6,7-dimethoxy-N2-methyl-N4-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine

References

1. Yan Xiong, et al. Bioorg Med Chem. 2017 Aug 15;25(16):4414-4423.

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MS3745 (MS 3745, MS-3745)

Biological Activity

Physicochemical Properties

References

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