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MS3745

Chemical Structure : MS3745

CAS No.: 2119601-41-9

MS3745 (MS 3745)

Catalog No.: PC-22923Not For Human Use, Lab Use Only.

MS3745 is a potent and selective inhibitor of protein lysine methyltransferase G9a-like protein (GLP) with IC50 of 4 nM, 65-fold selective over G9a.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MS3745 is a potent and selective inhibitor of protein lysine methyltransferase G9a-like protein (GLP) with IC50 of 4 nM, 65-fold selective over G9a.

Physicochemical Properties

M.Wt 399.54
Formula C22H33N5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N2-Cyclopentyl-6,7-dimethoxy-N2-methyl-N4-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine

References

1. Yan Xiong, et al. Bioorg Med Chem. 2017 Aug 15;25(16):4414-4423.

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