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Chemical Structure : MS436
CAS No.: 1395084-25-9
Catalog No.: PC-21330Not For Human Use, Lab Use Only.
MS436 is a potent, selective BRD4 BD1 bromodomain inhibitor with Ki values of 30-50 nM, 10-fold selectivity over the BD2.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $178 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $458 | In stock | |
| 100 mg | Get quote |
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MS436 is a potent, selective BRD4 BD1 bromodomain inhibitor with Ki values of 30-50 nM, 10-fold selectivity over the BD2.
MS436 effectively inhibits BRD4 activity in NF-κB-directed production of nitric oxide and pro-inflammatory cytokine interleukin-6 in murine macrophages.
| M.Wt | 383.43 | |
| Formula | C18H17N5O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(E)-4-((2-amino-4-hydroxy-5-methylphenyl)diazenyl)-N-(pyridin-2-yl)benzenesulfonamide |
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1. Zhang G, et al. J Med Chem. 2013 Nov 27;56(22):9251-64.
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