MS7972 |CAS:352553-42-5 Probechem Biochemicals

Chemical Structure : MS7972

CAS No.: 352553-42-5

MS7972 (MS-7972)

Catalog No.: PC-62280Not For Human Use, Lab Use Only.

MS7972 is a small molecules that blocks p53 and CREB binding protein (CBP) association, completely blocks CBP BRD/p53-AcK382 interactions at 50 uM, results in loss of p53 phosphorylation at Ser15 as well as acetylation at Lys382.

Packing	Price	Stock
5 mg	$148	In stock
10 mg	$228	In stock
25 mg	$388	In stock
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Biological Activity

MS7972 is a small molecules that blocks p53 and CREB binding protein (CBP) association, completely blocks CBP BRD/p53-AcK382 interactions at 50 uM, results in loss of p53 phosphorylation at Ser15 as well as acetylation at Lys382.
MS7972 causes a dramatic decrease of the doxorubicin-induced p53 increase in U2OS cells.

Physicochemical Properties

M.Wt	227.263
Formula	C14H13NO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	9-Acetyl-3,4-dihydro-2H-carbazol-1-one

References

1. Sachchidanand, et al. Chem Biol. 2006 Jan;13(1):81-90.

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MS7972 (MS-7972)

Biological Activity

Physicochemical Properties

References

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