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MT2 antagonist DH97

Chemical Structure : MT2 antagonist DH97

CAS No.: 220339-00-4

MT2 antagonist DH97

Catalog No.: PC-23431Not For Human Use, Lab Use Only.

DH97 is a potent and selective antagonist of MT2 melatonin receptor with pKi value of 8.03 for human MT2 receptor, shows 89- and 229-fold selectivity over human MT1 and Xenopus mel1c receptor subtypes.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DH97 is a potent and selective antagonist of MT2 melatonin receptor with pKi value of 8.03 for human MT2 receptor, shows 89- and 229-fold selectivity over human MT1 and Xenopus mel1c receptor subtypes.

Physicochemical Properties

M.Wt 334.46
Formula C22H26N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-pentanoyl-2-benzyltryptamine

References

1. Kojima S, et al. Br J Pharmacol. 2011 Mar;162(5):1179-85.

2. Teh MT, et al. Naunyn Schmiedebergs Arch Pharmacol.

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