MTEP

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Chemical Structure : MTEP

CAS No.: 329205-68-7

Catalog No.: PC-26041Not For Human Use, Lab Use Only.

MTEP is a potent, selective, non-competitive mGlu5 antagonist with IC50 of 5 nM and Ki of 16 nM.

Packing	Price	Stock
10 mg	$58	In stock
25 mg	$98	In stock
50 mg	$158	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MTEP is a potent, selective, non-competitive mGlu5 antagonist with IC50 of 5 nM and Ki of 16 nM.
MTEP produces antidepressant effects in several rodent models of depression.
MTEP also demonstrates neuroprotective potential by preventing excitotoxic neuronal damage.

Physicochemical Properties

M.Wt	200.26
Formula	C11H8N2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Methyl-4-(pyridin-3-ylethynyl)thiazole

References

1. Busse CS, et al. Neuropsychopharmacology. 2004 Nov;29(11):1971-9.

2. Keck TM, et al. ACS Med Chem Lett. 2012 Jul 12;3(7):544-549.

3. Rasmussen K, et al. Neuropharmacology. 2005 Feb;48(2):173-80.

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MTEP

Biological Activity

Physicochemical Properties

References

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