Chemical Structure : MTEP hydrochloride
CAS No.:
1186195-60-7
MTEP hydrochloride
(MTEP)
Catalog No. : PC-43392Not For Human Use, Lab Use Only.
MTEP hydrochloride is a potent, selective, non-competitive mGlu5 antagonist with IC50 of 5 nM and Ki of 16 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4339201
Biological Activity
MTEP hydrochloride is a potent, selective, non-competitive mGlu5 antagonist with IC50 of 5 nM and Ki of 16 nM.
Physicochemical Properties
M.Wt
236.7206
Formula
C11H9ClN2S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Pyridine, 3-[2-(2-methyl-4-thiazolyl)ethynyl]-, hydrochloride (1:1)
References
1. Busse CS, et al. Neuropsychopharmacology
2. Keck TM, et al. ACS Med Chem Lett.
3. Rasmussen K, et al. Neuropharmacology
4. Ossowska K, et al. Neuropharmacology
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