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Malabaricone C

Chemical Structure : Malabaricone C

CAS No.: 63335-25-1

Malabaricone C

Catalog No.: PC-23282Not For Human Use, Lab Use Only.

Malabaricone C is a natural sphingomyelin synthase (SMS) inhibitor with IC50 values of 3 uM and 1.5 μM for SMS1 and SMS2, respectively.

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Biological Activity

Malabaricone C is a natural sphingomyelin synthases (SMSs) inhibitor with IC50 values of 3 uM and 1.5 μM for SMS1 and SMS2, respectively. effectively suppresses male ESCC cell proliferation and xenograft tumor growth

Physicochemical Properties

M.Wt 358.43
Formula C21H26O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(2,6-Dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)nonan-1-one

References

1. Othman MA, et al. ACS Med Chem Lett. 2019;10(8):1154-1158.

2. Gong T, et al. Oncogene. 2024 Oct 23. doi: 10.1038/s41388-024-03193-z.

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