Malic Enzyme inhibitor ME1 |CAS:522649-59-8 Probechem Biochemicals

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Chemical Structure : Malic Enzyme inhibitor ME1

CAS No.: 522649-59-8

Malic Enzyme inhibitor ME1 (ME1)

Catalog No.: PC-35817Not For Human Use, Lab Use Only.

Malic Enzyme inhibitor ME1 (ME1) is a small molecule inhibitor of Malic Enzyme (ME1) with IC50 of 0.15 uM.

Packing	Price	Stock
10 mg	$158	In stock
25 mg	$248	In stock
50 mg	$388	In stock
100 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Malic Enzyme inhibitor ME1 (ME1) is a small molecule inhibitor of Malic Enzyme (ME1) with IC50 of 0.15 uM.
ME1 suppresses growth of human CRC cells in vitro, with little effect on normal rat intestinal epithelial cells.

Physicochemical Properties

M.Wt	351.406
Formula	C20H21N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-[4-(4-hydroxyphenyl)piperazin-1-yl]-1-phenylpyrrolidine-2,5-dione

References

1. Zhang YJ, et al. Bioorg Med Chem Lett. 2006 Feb;16(3):525-8.

2. Fernandes LM, et al. Sci Rep. 2018 Sep 24;8(1):14268.

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Malic Enzyme inhibitor ME1 (ME1)

Biological Activity

Physicochemical Properties

References

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