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Methotrexate

Chemical Structure : Methotrexate

CAS No.: 59-05-2

Methotrexate (Amethopterin, WR19039, CL14377)

Catalog No.: PC-26410Not For Human Use, Lab Use Only.

Methotrexate is antifolate agent and dihydrofolate reductase (DHFR) inhibitor.

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100 mg $38 In stock
250 mg $58 In stock
1 g $98 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Methotrexate is antifolate agent and dihydrofolate reductase (DHFR) inhibitor.

Physicochemical Properties

M.Wt 454.45
Formula C20H22N8O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-2-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid

References

1. Duch DS, et al. Cancer Res. 1979 Feb;39(2 Pt 1):487-91.

2. Hill BT, et al. Br J Cancer. 1973 Sep;28(3):263-8.

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