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Cat. No. Product Name CAS No. Information
PC-73018

DS18561882

2227149-22-4 DS18561882 (DS 18561882, DS18) is a potent, isozyme-selective, orally available MTHFD2 inhibitor with IC50 of 6.3 nM, >800-fold selectivity over MTHFD1.
PC-73015

DS44960156

2361327-08-2 DS44960156 (DS 44960156) is a isozyme-selective MTHFD2 inhibitor with IC50 of 1.6 uM, without inhibitory effect against MTHFD1 (IC50>30 uM).
PC-72940

TH9619

2379556-22-4 TH9619 (TH-9619) is a potent and selective inhibitor of folate metabolism enzyme MTHFD2 with IC50 of 47 nM.
PC-72939

TH9028

2379556-15-5 TH9028 (TH-9028) is a potent and selective inhibitor of folate metabolism enzyme MTHFD2 with IC50 of 11 nM.
PC-63364

TNP-351

125991-51-7 TNP-351 is an antifolate compound that functions as a DHFR inhibitor, strongly inhibits the growth of Meth A cells..
PC-62007

LSN 3213128

1941211-99-9 LSN 3213128 is a novel potent, selective and orally-bioavailable antifolate with potent and specific inhibitory activity for AICARFT.
PC-60506

Arfolitixorin

31690-11-6 A novel antifolate modulator compound..

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