TNP-351 | DHFR inhibitor DHFR inhibitor Probechem Biochemicals

Chemical Structure : TNP-351

Catalog No.: PC-63364Not For Human Use, Lab Use Only.

TNP-351 is an antifolate compound that functions as a DHFR inhibitor, strongly inhibits the growth of Meth A cells..

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Biological Activity

TNP-351 is an antifolate compound that functions as a DHFR inhibitor, strongly inhibits the growth of Meth A cells.

M.Wt	440.46
Formula	C21H24N6O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S)-2-[[4-[3-(2,4-diamino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)propyl]benzoyl]amino]pentanedioic acid

1. Itoh F, et al. Cancer Chemother Pharmacol. 1994;34(4):273-9.

2. Itoh F, et al. Chem Pharm Bull (Tokyo). 1995 Feb;43(2):230-5.