Catalog No.: PC-45788Not For Human Use, Lab Use Only.
Methoxsalen (8-Methoxypsoralen, Xanthotoxin, 8-MOP) is a potent tricyclic furocoumarin suicide that used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to sunlight.
Methoxsalen (8-Methoxypsoralen, Xanthotoxin, 8-MOP) is a potent tricyclic furocoumarin suicide that used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to sunlight.
Methoxsalen inhibits human CYP2A6 and mouse CYP2A5, inhibits nicotine metabolism and alters the behavioral effects of nicotine in the mouse.
Methoxsalen also induces Ca2+ entry in MG63 human osteosarcoma cells.
Physicochemical Properties
M.Wt
216.1895
Formula
C12H8O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
7H-Furo[3,2-g][1]benzopyran-7-one, 9-methoxy-
References
1. Lu YC, et al. Chin J Physiol. 2017 Jun 30;60(3):174-182.
2. Alsharari SD, et al. Nicotine Tob Res. 2014 Jan;16(1):18-25.
3. Bagdas D, et al. Neuropharmacology. 2014 Oct;85:67-72.
