Chemical Structure : Metoclopramide hydrochloride hydrate
CAS No.: 54143-57-6
Catalog No.: PC-45205Not For Human Use, Lab Use Only.
A potent dopamine D2 receptor antagonist with Ki of 28 nM.
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500 mg | $96 | In stock |
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A potent dopamine D2 receptor antagonist with Ki of 28 nM; also is a mixed 5-HT3 receptor antagonist/5-HT4 receptor agonist; commonly used to treat nausea and vomiting caused by chemotherapy.
Chemotherapeutic Agents
Phase 2 Discontinued
M.Wt | 354.2726 | |
Formula | C14H25Cl2N3O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, hydrochloride, hydrate (1:1:1) |
1. Matsui A, et al. J Pharmacol Exp Ther. 1998 Nov;287(2):725-32.
2. Tonini M, et al. Pharmacol Res. 1995 May;31(5):257-60.
3. Bateman DN, et al. Br J Clin Pharmacol. 1978 Nov;6(5):401-7.
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