Milategrast (E6007) | Cell adhesion inhibitor

Chemical Structure : Milategrast

Milategrast (E6007, E-6007)

Catalog No.: PC-28550Not For Human Use, Lab Use Only.

Milategrast (E6007) is a small molecule cell adhesion and cell infiltration inhibitor, inhibits the adhesion of Jurkat cells to human fibronectin with IC50 of <5 uM.

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Biological Activity

Milategrast (E6007) is a small molecule cell adhesion and cell infiltration inhibitor, inhibits the adhesion of Jurkat cells to human fibronectin with IC50 of <5 uM.

Physicochemical Properties

M.Wt	354.58
Formula	C24H38N2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(cyclopropylmethyl)-4-(2-(3,3,5,5-tetramethylcyclohexyl)phenyl)piperazine

References

1. Huang H, et al. Sci Adv. 2025 Jan 24;11(4):eadr8243.

2. Patent WO2006068058 A1.

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Milategrast (E6007, E-6007)

Biological Activity

Physicochemical Properties

References

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