Chemical Structure : Mocaciclib
CAS No.: 2766124-39-2
Catalog No.: PC-24960Not For Human Use, Lab Use Only.
Mocaciclib (Q901) is a highly selective and potent CDK7 inhibitor, forms a covalent bond with C312 of the CDK7 C-terminal domain.
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Mocaciclib (Q901) is a highly selective and potent CDK7 inhibitor, forms a covalent bond with C312 of the CDK7 C-terminal domain.
Mocaciclib (Q901) demonstrates selective cytotoxic activities in a broad spectrum of solid tumor lineages.
Mocaciclib (Q901) is compound 64 extracted from Patent WO2019197546 A1.
| M.Wt | 609.71 | |
| Formula | C33H36FN9O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-Fluoro-N-[1-[2-[[[2-[[[(3R,4R)-3-hydroxy-4-piperidinyl]methyl]amino]-8-(1-methylethyl)pyrazolo[1,5-a]-1,3,5-triazin-4-yl]amino]methyl]phenyl]-6-isoquinolinyl]-2-propenamide |
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1. Patent WO2019197546 A1.
2. Donghoon Yu, et al. Cancer Res (2022) 82 (12_Supplement): 2574.

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