Chemical Structure : Motixafortide
CAS No.:
664334-36-5
Motixafortide
(BL-8040, BKT-140, TF14016, 4F-Benzoyl-TN14003)
Catalog No. : PC-47505Not For Human Use, Lab Use Only.
Motixafortide (BL-8040, BKT-140, TF-14016) is a 14-residue biostable synthetic peptide, high-affinity CXCR4 antagonist (IC50=1 nM).
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4750501
Biological Activity
Motixafortide (BL-8040, BKT-140, TF-14016) is a 14-residue biostable synthetic peptide, high-affinity CXCR4 antagonist (IC50=1 nM).
Physicochemical Properties
M.Wt
2159.52
Formula
C97H144FN33O19S2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 36 mg/mL
Chemical Name/SMILES
L-Argininamide, N2-(4-fluorobenzoyl)-L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-D-lysyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic (4→13)-disulfide
References
1. Tamamura H, et al. FEBS Lett.
2. Peled A, et al. Clin Cancer Res.
3. Beider K, et al. Exp Hematol.
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