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Mpro61

Chemical Structure : Mpro61

CAS No.: 2679814-93-6

Mpro61 (SARS-CoV-2 Mpro inhibitor Mpro61)

Catalog No.: PC-22224Not For Human Use, Lab Use Only.

Mpro61 is a potent nanomolar inhibitor of SARS-CoV-2 Mpro with IC50 of 44 nM, antiviral EC50 of 80 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Mpro61 is a potent nanomolar inhibitor of SARS-CoV-2 Mpro with IC50 of 44 nM, antiviral EC50 of 80 nM.

Physicochemical Properties

M.Wt 565.38
Formula C28H19Cl2FN4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-(3-(3-chloro-5-((2-chlorobenzyl)oxy)-4-fluorophenyl)-2-oxo-2H-[1,3'-bipyridin]-5-yl)-1-methylpyrimidine-2,4(1H,3H)-dione

References

1. Chun-Hui Zhang, et al. ACS Med Chem Lett. 2021 Jul 14;12(8):1325-1332.

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