Catalog No.: PC-23986Not For Human Use, Lab Use Only.
Muscimol (Agarin) is a psychoactive isoxazole and selective neurotransmitter GABA agonist, binds GABAA on both high- and low-affinity sites (Kd=10 and 270 nM, respectively), stimulating chloride efflux with EC50 of 200 nM, also is a small molecule inhibitor of ninjurin-1 (NINJ1) oligomerization and NINJ1 mediated membrane rupture.
Muscimol (Agarin) is a psychoactive isoxazole and selective neurotransmitter GABA agonist, binds GABAA on both high- and low-affinity sites (Kd=10 and 270 nM, respectively), stimulating chloride efflux with EC50 of 200 nM, also is a small molecule inhibitor of ninjurin-1 (NINJ1) oligomerization and NINJ1 mediated membrane rupture.
Physicochemical Properties
M.Wt
114.10
Formula
C4H6N2O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
5-(aminomethyl)-1,2-oxazol-3-one
References
1. S M Dunn, et al. 1994 Jan 25;33(3):755-63.
2. den Hartigh AB, et al. Commun Biol. 2023 Oct 5;6(1):1010.
