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Chemical Structure : Myokinasib-II
Catalog No.: PC-23164Not For Human Use, Lab Use Only.
Myokinasib-II is a potent and highly selective myosin light-chain kinase (MLCK) chemical probe inhibitor with IC50 of 4.4 uM for MLCK-1.
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Myokinasib-II is a potent and highly selective myosin light-chain kinase (MLCK) chemical probe inhibitor with IC50 of 4.4 uM for MLCK1.
Myokinasib-II displays better potency, better selectivity profile, and no nonspecific interference in relevant assays as compared to other known MLCK inhibitors.
| M.Wt | 437.47 | |
| Formula | C24H24FN3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gautam Kumar, et al. ACS Chem Biol. 2024 Sep 20. doi: 10.1021/acschembio.4c00336.
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