N-CDPCB

Chemical Structure : N-CDPCB

Catalog No.: PC-23879Not For Human Use, Lab Use Only.

N-CDPCB is a small molecule inhibitor of fat mass and obesity associated protein (FTO), displays strong inhibitory activity of demethylation of the ssRNA by FTO with IC50 of 4.95 uM.

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Biological Activity

N-CDPCB is a small molecule inhibitor of fat mass and obesity associated protein (FTO), displays strong inhibitory activity of demethylation of the ssRNA by FTO with IC50 of 4.95 uM.
N-CDPCB (10 uM) inhibits FTO-mediated m6A modification of mRNA in preadipocytes (3T3-L1 cells).
N-CDPCB enhances m6A of mRNA of preadipocytes.

Physicochemical Properties

M.Wt	317.77
Formula	C17H16ClNO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-Chloro-2,4-dihydroxyphenyl)-1-phenylcyclobutanecarboxamide

References

1. He W, et al. J Med Chem. 2015 Sep 24;58(18):7341-8.

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N-CDPCB

Biological Activity

Physicochemical Properties

References

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