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N-Propargylglycine

Chemical Structure : N-Propargylglycine

CAS No.: 58160-95-5

N-Propargylglycine (N-PPG)

Catalog No.: PC-27844Not For Human Use, Lab Use Only.

N-propargylglycine (N-PPG) is a covalent, irreversible suicide inhibitor of proline dehydrogenase (PRODH), activates mitochondrial PRODH decay, shows anticancer activity and brain-enhancing mitohormesis properties

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Biological Activity

N-propargylglycine (N-PPG) is a covalent, irreversible suicide inhibitor of proline dehydrogenase (PRODH), activates mitochondrial PRODH decay, shows anticancer activity and brain-enhancing mitohormesis properties

Physicochemical Properties

M.Wt 113.12
Formula C5H7NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[(Prop-2-yn-1-yl)amino]acetic acid

References

1. Scott GK, et al. Amino Acids. 2021 Dec;53(12):1927-1939.

2. Scott GK, et al. Mol Cancer Ther. 2019 Aug;18(8):1374-1385.

3. White TA, et al. Biochemistry. 2008 May 20;47(20):5573-80.

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