N-oxalylglycine | 2OG oxygenase inhibitor

Chemical Structure : N-oxalylglycine

CAS No.: 5262-39-5

N-oxalylglycine (NOG, N-Oxaloglycine)

Catalog No.: PC-22621Not For Human Use, Lab Use Only.

N-oxalylglycine (NOG) is a broad-spectrum 2OG oxygenase inhibitor with IC50 of 0.36 uM, 12.3 uM, 11.1 uM and 0.15 uM for FIH, PHD2, aspartate/asparagine-β-hydroxylase (AspH) and JMJD5, respectively.

Packing	Price	Stock
100 mg	$58	In stock
250 mg	$88	In stock
500 mg	$128	In stock
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Biological Activity

N-oxalylglycine (NOG) is a broad-spectrum 2OG oxygenase inhibitor with IC50 of 0.36 uM, 12.3 uM, 11.1 uM and 0.15 uM for FIH, PHD2, aspartate/asparagine-β-hydroxylase (AspH) and JMJD5, respectively.

Physicochemical Properties

M.Wt	147.09
Formula	C4H5NO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((Carboxymethyl)amino)-2-oxoacetic acid

References

1. Thomas P Corner, et al. Chem Sci. 2023 Oct 27;14(43):12098-12120.

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N-oxalylglycine (NOG, N-Oxaloglycine)

Biological Activity

Physicochemical Properties

References

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