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N19-0881

Chemical Structure : N19-0881

CAS No.: 1613410-75-5

N19-0881 (KDM5-N19, N 19-0881)

Catalog No.: PC-22359Not For Human Use, Lab Use Only.

KDM5-N19 (N19-0881) is a potent, selective, αKG-competitive KDM5B inhibitor with IC50 of 2 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

KDM5-N19 (N19-0881) is a potent, selective, αKG-competitive KDM5B inhibitor with IC50 of 2 nM.

Physicochemical Properties

M.Wt 343.77
Formula C17H14ClN3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(5-((4-chloro-2-methylbenzyl)oxy)-1H-pyrazol-1-yl)isonicotinic acid

References

1. Horton JR, et al. Cell Chem Biol. 2016 Jul 21;23(7):769-781.

2. Kai Tang, et al. J Med Chem. 2022 Oct 13;65(19):12979-13000.

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