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N6-cyclopentyladenosine

Chemical Structure : N6-cyclopentyladenosine

CAS No.: 41552-82-3

N6-cyclopentyladenosine (CPA, UK-80882)

Catalog No.: PC-27870Not For Human Use, Lab Use Only.

N6-Cyclopentyladenosine (CPA) is a high affinity, selective adenosine A1 receptor (A1R) agonist with Ki of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

N6-Cyclopentyladenosine (CPA) is a high affinity, selective adenosine A1 receptor (A1R) agonist with Ki of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively.

Physicochemical Properties

M.Wt 335.36
Formula C15H21N5O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2R,3R,4S,5R)-2-(6-(Cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

References

1. Klotz KN, et al. Naunyn Schmiedebergs Arch Pharmacol. 2000 Nov;362(4-5):382-91.

2. Pospísil M, et al. Eur J Pharmacol. 2005 Jan 10;507(1-3):1-6.

3. Mathôt RA, et al. J Pharmacol Exp Ther. 1994 Feb;268(2):616-24.

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