NAMI-A |CAS:201653-76-1 Probechem Biochemicals

Chemical Structure : NAMI-A

NAMI-A

Catalog No.: PC-45629Not For Human Use, Lab Use Only.

A ruthenium anticancer agent that has a selective effect on lung metastases of solid metastasizing tumors.

Packing	Price	Stock	Quantity
5 mg		Get quote
10 mg		Get quote
25 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

NAMI-A is a ruthenium anticancer agent that has a selective effect on lung metastases of solid metastasizing tumors, inhibits the matrix metallo-proteinases MMP-2 and MMP-9 at micromolar concentrations.
NAMI-A significantly affects tumor cells with metastatic ability.
NAMI-A decreases the α5β1 integrin expression, and reduces FAK auto-phosphorylation on Tyr397 in HCT-116 colorectal cancer cells.

Physicochemical Properties

M.Wt	458.18
Formula	C5H10Cl4N2ORuS . C3H4N2 . H
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	H2O: 8.28 mg/mL
Chemical Name/SMILES	Ruthenate(1-), tetrachloro(1H-imidazole-κN3)[1,1'-(sulfinyl-κS)bis[methane]]-, (OC-6-11)-, hydrogen, compd. with 1H-imidazole (1:1:1)

References

1. Pelillo C, et al. J Inorg Biochem. 2016 Jul;160:225-35.

2. Sava G, et al. Clin Cancer Res. 2003 May;9(5):1898-905.

3. Frausin F, et al. J Pharmacol Exp Ther. 2005 Apr;313(1):227-33.

NAMI-A

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.